Current topics in microbiology and immunology. 0070-217X ; 327.
Nanobiotechnology involves the exploitation of biomaterials, devices or methodologies at the nanoscale. Virus particles are natural nanomaterials and have received particular attention as novel building blocks for materials design and fabrication. In this volume, leaders in the field of viral nanobiotechnology address the fundamental means for generating virus-based nanoparticles by performing chemistry on virion substrates, multilayered arrays and hybrid virus networks incorporating materials such as quantum dots and carbon nanotubes. The use of virus-like protein cages to generate novel materials that can be used for biomedical applications such as biomedical imaging and vaccine purposes is discussed. Finally, the novel tumor-targeting properties of certain viruses are harnessed to achieve specificity in vivo. This volume describes the unprecedented opportunities to capitalize on the vast knowledge of virus particles and their physical and material properties.
Formatted Contents Note
Introduction: Marianne Manchester and Nicole F. Steinmetz Chapter 1: Chemical modification of viruses and virus-like particles by Erica Strable and M.G. Finn Chapter 2: Structure-based Engineering of an Icosahedral Virus for Nano-medicine and -technology by Nicole F. Steinmetz, Tianwei Lin, George P. Lomonossoff, and John E. Johnson Chapter 3: Hybrid Assembly of CPMV Viruses and Surface Characteristics of Different Mutants by Nathaniel G. Portney, Giuseppe Destito, Marianne Manchester, and Mihrimah Ozkan.-Chapter 4: A Library of Protein Cage Architectures as Nanomaterials by Michelle L. Flenniken, Masaki Uchida, Lars O. Liepold, Sebyung Kang, Mark J. Young, and Trevor Douglas Chapter 5: Biomedical nanotechnology using virus-based nanoparticles by Giuseppe Destito, Anette Schneemann, and Marianne Manchester Chapter 6: Tumor targeting using canine parvovirus nanoparticles by Pratik Singh Subject index.
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