"This title was first published in 2003: As new medical technologies and treatments develop with increasing momentum, the legal and ethical implications of research involving human participants are being called into question as never before. Human Experimentation and Research explores the philosophical foundations of research ethics, ongoing regulatory dilemmas, and future challenges raised by the rapid globalisation and corporatisation of the research endeavour. This volume brings together some of the most significant published essays in the field. The editors also provide an informative introduction, summarizing the area and the relevance of the articles chosen."--Provided by publisher.
First published 2001 by Ashgate Publishing.
Formatted Contents Note
part, I The Historical and Philosophical Foundations chapter 1 Philosophical Reflections on Experimenting with Human Subjects / Hans Jonas chapter 2 Experimenting on Human Subjects: Philosophical Perspectives * / Ruth Macklin Susan Sherwin chapter 3 Principlism and the Ethical Appraisal of Clinical Trials / Eric M. Meslin Heather J. Sutherland James V. Lavery James E. Till chapter 4 Nuremberg Code in Light of Previous Principles and Practices in Human Experimentation / David Rothman chapter 5 's Legacy Some Ethical Reflections / James Childress* chapter 6 Controversy over Retrospective Moral Judgment / Allen Buchanan chapter 7 Back and Judging Our Predecessors / Tom L. Beauchamp chapter 8 When Evil Intrudes / Arthur L. Caplan chapter 9 Shading the Truth in Seeking Informed Consent for Research Purposes* / Sissela Bok chapter 10 The Fragile Foundation of Contemporary Biomedical Research / Nancy E. Kass Jeremy Sugarman Ruth Faden Monica Schoch-Spana chapter 11 for Grails: Duplicity, Betrayal and Self-Deception in Postmodern Medical Research / George J. Annas chapter 12 Roles and Fictions in Clinical and Research Ethics / David N. Weisstub part, II Protecting Human Subjects chapter 13 Human Experimentation and Human Rights* / Jay Katz chapter 14 The Social Control Of Human Biomedical Research: An Overview and Review of the Literature / Paul R. Benson chapter 15 Goodbye to All That The End of Moderate Protectionism in Human Subjects Research / Jonathan D. Moreno chapter 16 Is National, Independent Oversight Needed for the Protection of Human Subjects? / Alexander Morgan Capron chapter 17 National, Independent Oversight: Reinforcing the Safety Net for Human Subjects Research* / Anna C. Mastroianni chapter 18 Regulating Research for the Decisionally Impaired: Implications for Mental Health Professionals / Marshall B. Kapp chapter 19 Are Research Ethics Bad for Our Mental Health? / Robert Michels chapter 20 The Reform of Adult Guardianship Laws: The Case of Non-Therapeutic Experimentation / George F. Tomossy David N. Weisstub part, III Risk and Responsibility chapter 21 The Ethical Analysis of Risk / Charles Weijer chapter 22 Defining and Describing Benefit Appropriately in Clinical Trials / Nancy M. P. King chapter 23 What Research With Stored Samples Teaches Us About Research With Human Subjects / David Wendler chapter 24 Uncertainty in Clinical Research / Robert J. Levine chapter 25 Equipoise And The Ethics Of Clinical Research / Benjamin Freedman chapter 26 Equipoise, Knowledge And Ethics In Clinical Research And Practice / Richard Ashcroft chapter 27 Ethical considerations concerning treatment allocation in drug development trials / S. Senn chapter 28 Are Placebo-Controlled Trials No Longer Appropriate? / Baruch A. Brody part, IV and Corporation - Trust and Participation chapter 29 Research: Ethical or Ethical Pluralism? 1 / Ruth Macklin* chapter 30 Academic Medicine for Sale? / Marcia Angell chapter 31 Issues in Research Relationships Between Universities and Industry 1 / James T. Rule Adil E. Shamoo chapter 32 Alliance Clinical Investigators and the Pharmaceutical Industry / Thomas Bodenheimer chapter 33 Review for Sale? Conflict of Interest and Commercial Research Review Boards / Trudo Lemmens Benjamin Freedman chapter 34 Dealing with Conflicts of Interest in Biomedical Research: IRB Oversight as the Next Best Solution to the Abolitionist Approach / Jesse A. Goldner chapter 35 Restoring and Preserving Trust in Biomedical Research / Mark Yarborough Richard R. Sharp chapter 36 Privatized Biomedical Research, Public Fears, and the Hazards of Government Regulation: Lessons from Stem Cell Research / David B. Resnik.